Throughout the biological and biomedical sciences there is a growing need for, prescriptive ‘minimum information’ (MI) checklists specifying the key information to include when reporting experimental results are beginning to find favor with experimentalists, analysts, publishers and funders alike. Such checklists aim to ensure that methods, data, analyses and results are described to a level sufficient to support the unambiguous interpretation, sophisticated search, reanalysis and experimental corroboration and reuse of data sets, facilitating the extraction of maximum value from data sets (...) them. However, such ‘minimum information’ MI checklists are usually developed independently by groups working within representatives of particular biologically- or technologically-delineated domains. Consequently, an overview of the full range of checklists can be difficult to establish without intensive searching, and even tracking thetheir individual evolution of single checklists may be a non-trivial exercise. Checklists are also inevitably partially redundant when measured one against another, and where they overlap is far from straightforward. Furthermore, conflicts in scope and arbitrary decisions on wording and sub-structuring make integration difficult. This presents inhibit their use in combination. Overall, these issues present significant difficulties for the users of checklists, especially those in areas such as systems biology, who routinely combine information from multiple biological domains and technology platforms. To address all of the above, we present MIBBI (Minimum Information for Biological and Biomedical Investigations); a web-based communal resource for such checklists, designed to act as a ‘one-stop shop’ for those exploring the range of extant checklist projects, and to foster collaborative, integrative development and ultimately promote gradual integration of checklists. (shrink)

This is a critical survey of writing on the philosophy of photography.

If an artist sends a live peacock to an exhibition, is it art? 'What is art?' is a question many of us want answered but are too afraid to ask. It is the very question that Nigel Warburton demystifies in this brilliant and accessible little book. With the help of varied illustrations and photographs, from Cézanne and Francis Bacon to Andy Warhol and Damien Hirst, best-selling author Warburton brings a philosopher's eye to art in a refreshing jargon-free style. With (...) customary clarity, he explains art theories, that are much discussed but little understood, by thinkers such as Clive Bell, R.G Collingwood and Wittgenstein. He illuminates other perplexing problems in art, such as the artist's intention, representation and emotion. Drawing on photographs of Cindy Sherman and Tiananmen Square, Warburton shows that, if we are ever to answer the art question, we must consider each work of art on its own terms. A stimulating and handy guide through the art maze, The Art Question is essential reading for anyone interested in art, philosophy or those who simply like looking at and thinking about pictures. (shrink)

Unlike topics such as criminal responsibility, dangerousness has only recently begun to interest philosophically minded penologists. The most likely explanation is that until the middle of this century the periods for which people who had done serious harm to others were incarcerated in the UK so long that when they were released their age or condition or circumstances made them unlikely to repeat their crimes. It was only when pressure of resources—in plain terms overcrowded prisons and mental hospitals—forced the shortening (...) of these periods that it became politically necessary to worry about the possible dangerousness of really substantial numbers of prisoners and patients who became eligible for release. The problem was not entirely new. A few lifers, for example, had been set free each year, under licences which lasted for the rest of their lives; and the Special Hospitals which housed the violent insane had discharged carefully selected inmates, also under supervision. But by the late 1960s the introduction of parole, the Mental Health Act and the abolition of capital punishment had greatly increased the number of cases in which the problem of dangerousness had to be faced, and difficult decisions had to be taken. (shrink)

One important problem in the philosophy of science is whether there can be a normative theory of discovery, as opposed to a normative theory of justification. Although the possibility of developing a logic of scientific discovery has been often doubted by philosophers, it is particularly interesting to consider how the basic insights of a normative theory of discovery have been turned into an effective research program in computer science, namely the research field of machine learning. In this paper, I introduce (...) some current research on statistical models to a philosophical audience. In particular, I will stress those features of statistical models that make them plausible computational counterparts of scientific theories. After noticing how these models allow for the main kinds of inference that are a trademark of scientific theories, I will focus on the problem of learning statistical models from data. The analysis will show how machine learning is casting new light on traditional problems in the philosophy of science. More precisely, I will explore the implications of some results in statistical learning with respect to the role of simplicity in theory choice and to the role of scalability (as a formal property of induction) in making scientific discovery effective. (shrink)

What is the fruit of a searching dialogue between faith and reason? This book collects theological and philosophical perspectives on the richness of the faith-reason dialogue, including examples from literature, continental and analytic philosophy, worship and liturgy, and radical approaches to issues of racism and prejudice. The authors strongly resist the temptations to either disregard the faith-reason dialogue or take it for granted. Through their explorations and reflections they open up new vistas and horizons on a topic more necessary than (...) ever. (shrink)

When Ron Giere introduced perspectivism into philosophy of science, he provided a perspectivist analysis of both scientific instruments and scientific theorizing. Today, there is a burgeoning literature that extends Giere’s analysis of theorizing, with many philosophers examining the perspectivist approach to aspects of theorizing such as models, laws, explanations, and so on. However, relatively little attention has been paid to Giere’s analysis of instruments. In this article, I hope to fill this gap. I argue that the perspectivist analysis of instruments (...) should be rejected. First, I give a general account of the kind of instrumentation relevant to instrumental perspectivism, drawing on Cartwright’s notion of nomological machines, which forms the basis of my criticism of Giere’s argument for instrumental perspectivism. Next, I present the case against instrumental perspectivism. I argue that instrumental perspectivism is dependent on theoretical perspectivism in a way that robs it of philosophical significance, and that it introduces new puzzles while adding little to our understanding of instruments. (shrink)

Robert Kane provides a critical overview of debates about free will of the past half century, relating this recent inquiry to the broader history of the free will issue and to vital currents of twentieth century thought. Kane also defends a traditional libertarian or incompatibilist view of free will, employing arguments that are both new to philosophy and that respond to contemporary developments in physics and biology, neuro science, and the cognitive and behavioral sciences.

Cognitive science has always included multiple methodologies and theoretical commitments. The philosophy of cognitive science should embrace, or at least acknowledge, this diversity. Bechtel’s (2009a) proposed philosophy of cognitive science, however, applies only to representationalist and mechanist cognitive science, ignoring the substantial minority of dynamically oriented cognitive scientists. As an example of nonrepresentational, dynamical cognitive science, we describe strong anticipation as a model for circadian systems (Stepp & Turvey, 2009). We then propose a philosophy of science appropriate to nonrepresentational, dynamical (...) cognitive science. (shrink)

According to constructive empiricists, accepting a scientific theory involves belief only that it is true of the observable world, where observability is defined in terms of what is detectable by the unaided senses. On this view, scientific instruments are machines that generate new observable data, but this data need not be interpreted as providing access to a realm of phenomena beyond what is revealed by the senses. A recent challenge to the constructive empiricist account of instruments appeals to the extended (...) mind thesis, according to which cognitive processes are sometimes constituted not just by brain activity, but can extend into the rest of the body and the surrounding environment. If this is right, scientific instruments may, in the right circumstances, literally become part of our perceptual processes. In this article, I examine this extended perception argument, and I find that it fails for the vast majority of scientific instruments. Even if the extended mind thesis is accepted, the constructive empiricist can draw a line between observables and unobservables that makes very few concessions to the realist. (shrink)

Timely and much-needed theory of humanity's relation to the planet.

We attempt in this paper to define a new field of study for philosophy: philosophy of management. We briefly speculate why the interest some managers and management writers take in philosophy has been so little reciprocated and why it needs to be. Then we suggest the scope of this new branch of philosophy and how it relates to and overlaps with other branches. We summarise some key matters philosophers of management should concern themselves with and pursue one in some detail. (...) We conclude with an invitation. (shrink)

The 'postmodern condition,' in which instrumentalism finally usurps all other considerations, has produced a kind of intellectual paralysis in the world of education. The authors of this book show how such postmodernist thinkers as Derrida, Foucault, and Lyotard illuminate puzzling aspects of education, arguing that educational theory is currently at an impasse. They postulate that we need these new and disturbing ideas in order to "think again" fruitfully and creatively about education.

How can we register the participation of a range of elements, extending beyond the human subject, in the production of HIV events? In the context of proposals around biomedical prevention, there is a growing awareness of the need to find ways of responding to complexity, as everywhere new combinations of treatment, behavior, drugs, norms, meanings and devices are coming into encounter with one another, or are set to come into encounter with one another, with a range of unpredictable effects. In (...) this paper I consider the operation of various framing devices that attribute responsibility and causation with regard to HIV events. I propose that we need to sharpen our analytic focus on what these devices do, their performativity—that is, their full range of worldly implications and effects. My primary examples are the criminal law and the randomized control trial. I argue that these institutions operate as framing devices: They attribute responsibility for HIV events and externalize other elements and effects in the process. Drawing on recent work in science and technology studies as well as queer theory, I set out an analytic frame that marks out a new role for HIV social research. Attentiveness to the performative effects of these devices is crucial, I suggest, if we want better to address the global HIV epidemic. (shrink)

This timely book addresses concerns about educational and moral standards in a world characterised by a growing nihilism.

Talk of “essences” has, since Saul Kripke and Hilary Putnam, gained significant currency in contemporary philosophy. It is no longer unfashionable to talk about the essence of this or that (natural) kind, and as such we now find a variety of brands of essentialism on the market including B.D. Ellis’s scientific essentialism, David Oderberg’s real Essentialism, Alexander Bird’s dispositional essentialism, and the contemporary essentialism of Kripke and Putnam. -/- Almost all these brands of essentialism share a particular gloss on Locke’s (...) famous objection to Aristotle that natural kinds are demarcated by nominal essences not real essences. Thus Oderberg claims that ‘Empiricists take [real] essences to be paradigmatically unobservable’ and that this ‘objection goes back at least to John Locke’ (Oderberg 2007: 21). Bird, presenting his dispositional essentialism, defines a notion of “being” as ‘the reverse of Locke’s definition of essence’ which he takes to be ‘the being of any thing, whereby it is what it is’ (Bird 2007: 100). Joseph LaPorte, discussing nominal and real essences, claims that ‘Kripke and Putnam seem to affirm something more substantive: that biological kinds have “real essences” in Locke’s terminology’ (LaPorte 2004: 49). Even avowed anti-essentialists such as John Dupré sanction the standard criticism of Locke that his scepticism about the knowability of real essences was ‘premature’, and claim that ‘genuine natural kinds provide the extensions of many terms of natural language, where these natural kinds are determined by true Lockean real essences’ (Dupré 1993: 22). -/- All of these essentialisms (even Dupré’s anti-essentialism) are wrong about Locke. Oderberg is wrong to claim that Locke thought that real essences were paradigmatically unobservable; Bird is wrong to think that Locke’s notion of essence is the being of anything whereby it is what it is; LaPorte is wrong to think that Kripke and Putnam are talking about Lockean real essences (although so are Kripke and Putnam); and Dupré is wrong to think that genuine natural kinds (if by genuine he means objective or mind-independent) are determined but true Lockean real essences . -/- The mistake stems from a standard, but ultimately incorrect, interpretation of Locke’s discussion of essences in An Essay Concerning Human Understanding . This mistaken interpretation (Lowe 1995, 2006, Von Leyden 1973, Wiggins 1974) takes Locke to mean, by “real essence”, the Aristotelian notion i.e. ‘the very being of anything, whereby it is what it is’ (Essay III.iii.15), and interprets his objection as epistemological: we cannot come to know what real essences are, and therefore they cannot figure in our classifications of things into kinds. -/- This paper will present and defend the following two claims: i) that Locke’s notion of “real essence” is not the Aristotelian notion, and ii) that Locke’s objection to the Aristotelian notion was not merely epistemological. The first claim can be defended by presenting and applying Vienne’s (1993) terminological revision. Vienne argues that Locke did not introduce a dichotomy between real and nominal essence, but a trichotomy between real essence, nominal essence and real constitution. This terminological revision will be employed to highlight where ambiguous uses of the phrase “real essence” have caused some serious misunderstandings of Locke’s philosophy. The second claim (steering Locke around what is the classic objection to his thesis) can be defended by presenting a novel way of splitting up Locke’s objections to the Aristotelian notion of essence. The analysis will show that Locke’s anti-essentialism is still in good shape, and of contemporary significance. (shrink)

Theology is based on God's true and unchanging Word, but does it supply an unwavering foundation for spiritual certainties? Brush contends that it does not, because, like science, theology is a human discipline and subject to our limitations of knowledge, interpretation, and objectivity. In part one, Brush unpacks this contention, showing how Christians both past and present have arrived at conclusions that actually run counter to biblical teaching, and how these interpretive viewpoints have changed over time. In part two, he (...) makes the case that flawed theological positions have resulted in views that needlessly conflict with science, and that these clashes can be resolved with more accurate formulations. Brush evenly evaluates questions including the age of the earth, the origin of life, and the end of time."--Publisher. (shrink)

This paper challenges the notion that Bitcoin is ‘trust-free’ money by highlighting the social practices, organizational structures and utopian ambitions that sustain it. At the paper's heart is the paradox that if Bitcoin succeeds in its own terms as an ideology, it will fail in practical terms as a form of money. The main reason for this is that the new currency is premised on the idea of money as a ‘thing’ that must be abstracted from social life in order (...) for it to be protected from manipulation by bank intermediaries and political authorities. The image is of a fully mechanized currency that operates over and above social life. In practice, however, the currency has generated a thriving community around its political ideals, relies on a high degree of social organization in order to be produced, has a discernible social structure, and is characterized by asymmetries of wealth and power that are not dissimilar from the mainstream financial system. Unwittingly, then, Bitcoin serves as a powerful demonstration of the relational character of money. (shrink)

This study of the implications of Gillick competence argues it is an unnecessary burden with an unethical foundation. The ethics of adolescent medical decision-making is a fraught area for medical ethics because it deals with the threshold boundaries between childhood and adulthood and Gillick adds a burden upon children and adolescent patients that is unwarranted and through which damage is done to integral human relationships. In light of Gillick, it can be seen that the context of adolescent decision-making and childhood, (...) is a neglected topic of ethical reflection. (shrink)

This introduction outlines the importance that Hans-Georg Backhaus’s transcript of Adorno’s 1962 seminar on ‘Marx and the Basic Concepts of Sociological Theory’ has for shedding light on the relationship between Adorno’s critical theory and the critique of political economy. PartIsignals the importance of the seminar by assaying the Anglophone scholarship on Adorno. PartIIcontextualises the seminar in the development of his thought. PartsIIIandIVfocus on what the transcript tells us about Adorno’s interpretation of Marx and the importance this interpretation held for Adorno’s (...) critical social theory. PartVpoints to the influence this interpretation of the critique of political economy had on the formation of the New German Reading of Marx. (shrink)

Theories of superior collicular and hippocampal function have remarkable similarities. Both structures have been repeatedly implicated in spatial and attentional behaviour and in inhibitory control of locomotion. Moreover, they share certain electrophysiological properties in their single unit responses and in the synchronous appearance and disappearance of slow wave activity. Both are phylogenetically old and the colliculus projects strongly to brainstem nuclei instrumental in the generation of theta rhythm in the hippocampal EECOn the other hand, close inspection of behavioural and electrophysiological (...) data reveals disparities. In particular, hippocampal processing mainly concerns stimulus ambiguity, contextual significance, and spatial relations or other subtle, higher order characteristics. This requires the use of largely preprocessed sensory information and mediation of poststimulus investigation. Although collicular activity must also be integrated with that of “higher” centres, its primary role in attention is more “peripheral” and specific in controlling orienting/localisation via eye and body movements toward egocentrically labelled spatial positions. In addition, the colliculus may exert a nonspecific influence in alerting higher centres to the imminence of information potentially worthy of focal attention. Nevertheless, it is noteworthy that collicular and hippocampal lesions produce deficits on similar tasks, although the type of deficit is usually different in each case. Functional overlap between hippocampus and colliculus is virtually certain vis-à-vis stimulus sampling, for example in the acquisition of information via vibrissal movements and visual scanning. In addition, insofar as stimulus significance is a factor in collicular orienting mechanisms, the hippocampus — cingulate – cortex — colliculus pathway may play a significant role, modulating collicular responsiveness and thus ensuring an attentional strategy appropriate to current requirements. A tentative “reciprocal loop” model is proposed which bridges physiological and behavioural levels of analysis and which would account for the observed degree and nature of functional overlap between the superior colliculus and hippocampus. (shrink)

This comprehensive reference provides an exhaustive guide to current scholarship on the perennial problem of Free Will--perhaps the most hotly and voluminously debated of all philosophical problems. While reference is made throughout to the contributions of major thinkers of the past, the emphasis is on recent research. The essays, most of which are previously unpublished, combine the work of established scholars with younger thinkers who are beginning to make significant contributions. Taken as a whole, the Handbook provides an engaging and (...) accessible roadmap to the state of the art thinking on this enduring topic. (shrink)

Focusing on the concepts and interactions of free will, moral responsibility, and determinism, this text represents the most up-to-date account of the four major positions in the free will debate. Four serious and well-known philosophers explore the opposing viewpoints of libertarianism, compatibilism, hard incompatibilism, and revisionism The first half of the book contains each philosopher’s explanation of his particular view; the second half allows them to directly respond to each other’s arguments, in a lively and engaging conversation Offers the reader (...) a one of a kind, interactive discussion Forms part of the acclaimed Great Debates in Philosophy series. (shrink)

This work has been selected by scholars as being culturally important and is part of the knowledge base of civilization as we know it. This work is in the public domain in the United States of America, and possibly other nations. Within the United States, you may freely copy and distribute this work, as no entity has a copyright on the body of the work. Scholars believe, and we concur, that this work is important enough to be preserved, reproduced, and (...) made generally available to the public. To ensure a quality reading experience, this work has been proofread and republished using a format that seamlessly blends the original graphical elements with text in an easy-to-read typeface. We appreciate your support of the preservation process, and thank you for being an important part of keeping this knowledge alive and relevant. (shrink)

Adorno: A Critical Reader presents a collection of new essays by many of the world's top critics that examine Adorno's lasting impact on the arts, politics, history, philosophy, psychoanalysis, and sociology.

This book uses the philosophy of Wittgenstein as a perspective from which to challenge the idea of a critical social theory, represented pre-eminently by Giddens, Habermas and Bhaskar.

__‘Philosophy: The Basics deservedly remains the most recommended introduction to philosophy on the market. Warburton is patient, accurate and, above all, clear. There is no better short introduction to philosophy.’_ - Stephen Law, author of The Philosophy Gym_ _Philosophy: The Basics_ gently eases the reader into the world of philosophy. Each chapter considers a key area of philosophy, explaining and exploring the basic ideas and themes including: Can you prove God exists? How do we know right from wrong? What are (...) the limits of free speech? Do you know how science works? Is your mind different from your body? Can you define art? How should we treat non-human animals? For the fifth edition of this best-selling book, Nigel Warburton has added an entirely new chapter on animals, revised others and brought the further reading sections up to date. If you’ve ever asked ‘what is philosophy?’, or wondered whether the world is really the way you think it is, this is the book for you. (shrink)

This book argues that the institutions of law, and the structures of legal thought, are to be understood by reference to a moral ideal of freedom or independence from the power of others. The moral value and justificatory force of law are not contingent upon circumstance, but intrinsic to its character. Doctrinal legal arguments are shaped by rival conceptions of the conditions for realization of the idea of law. In making these claims, the author rejects the viewpoint of much contemporary (...) legal theory, and seeks to move jurisprudence closer to an older tradition of philosophical reflection upon law, exemplified by Hobbes and Kant. Modern analytical jurisprudence has tended to view these older philosophies as confused precisely in so far as they equate an understanding of law's nature with a revelation of its moral basis. According to most contemporary legal theorists, the understanding and analysis of existing institutions is quite distinct from any enterprise of moral reflection, but the relationship between ideals and practices is much more intimate than this approach would suggest. Some institutions can be properly understood only when they are viewed as imperfect attempts to realize moral or political ideals; and some ideals can be conceived only by reference to their expression in institutions. (shrink)

The first book to look architectural narrative in the eye Since the early eighties, many architects have used the term "narrative" to describe their work. To architects the enduring attraction of narrative is that it offers a way of engaging with the way a city feels and works. Rather than reducing architecture to mere style or an overt emphasis on technology, it foregrounds the experiential dimension of architecture. Narrative Architecture explores the potential for narrative as a way of interpreting buildings (...) from ancient history through to the present, deals with architectural background, analysis and practice as well as its future development. Authored by Nigel Coates, a foremost figure in the field of narrative architecture, the book is one of the first to address this subject directly Features architects as diverse as William Kent, Antoni Gaudí, Eero Saarinen, Ettore Sottsass, Superstudio, Rem Koolhaas, and FAT to provide an overview of the work of NATO and Coates, as well as chapters on other contemporary designers Includes over 120 colour photographs Signposting narrative's significance as a design approach that can aid architecture to remain relevant in this complex, multi-disciplinary and multi-everything age, Narrative Architecture is a must-read for anyone with an interest in architectural history and theory. (shrink)

A short story exploring cloning and the Teletransporter Thought Experiment. Rather than abstract consideration, the focus is on the first-personal experience.

In a recent paper in this journal, “How should libertarians conceive of the location and role of indeterminism?” Christopher Evan Franklin critically examines my libertarian view of free will and attempts to improve upon it. He says that while Kane's influential [view] offers many important advances in the development of a defensible libertarian theory of free will and moral responsibility … [he made] “two crucial mistakes in formulating libertarianism” – one about the location of indeterminism, the other about its (...) role – “both of which have helped fan the flame of the luck argument”. In this paper, I respond to Franklin's criticisms, arguing that, so far from making it significantly more difficult to answer objections about luck and control, as he claims, giving indeterminism the location and role I do makes it possible to answer such objections and many other related objections to libertarian free will. A central theme of this paper will emerge in my responses: In order to make sense of freedom of will... (shrink)

Abstractα/β barrels have an ill‐defined origin. Evidence exists which favours their divergent evolution from a common ancestral barrel and convergent evolution to a stable fold. However, recent sequence and structural information for the flavin oxidase/dehydrogenase family of barrel enzymes indicate that sub‐families of α/β barrels have evolved divergently. The modular fusion of barrel domains with core structures from other gene families has also contributed to the evolution of related but catalytically distinct enzyme molecules within each sub‐family of the flavin oxidases/dehydrogenases. (...) An analysis of the structures and sequences of the flavin oxidases/dehydrogenases has now enabled studies focusing on the evolutionary origins and modular assembly of this important family of proteins to be initiated. (shrink)

This ambitious work apparently has two main aims. The first is to provide a survey of the currently burgeoning field of "Consciousness Studies", presented via the extended metaphor of a horse race whose winning post is a full scientific explanation of consciousness. The second, which receives much more space, is to present Taylor's own cognitive/neuroscientific theory, dubbed "relational consciousness", and to persuade us that it should be the odds-on favourite to win. Neither aim is very well realized.

This book addresses concerns about educational and moral standards in a world increasingly characterised by nihilism. On the one hand there is widespread anxiety that standards are falling; on the other, new machinery of accountability and inspection to show that they are not. The authors in this book state that we cannot avoid nihilism if we are simply _laissez-faire_ about values, neither can we reduce them to standards of performance, nor must we return to traditional values. They state that we (...) need to create a new set of values based on a critical assessment of contemporary practice in the light of a number of philosophical texts that address the question of nihilism, including the work of Nietzsche. (shrink)

Against the domination of moral deliberation by rights-talk In Defence of War asserts that belligerency can be morally justified, even while it is tragic and morally flawed. Recovering the early Christian tradition of just war thinking, Nigel Biggar argues in favour of aggressive war in punishment of grave injustice.

Fire is a force that links everyday human activities to some of the most powerful energetic movements of the Earth. Drawing together the energy-centred social theory of Georges Bataille, the fire-centred environmental history of Stephen Pyne, and the work of a number of ‘pyrotechnology’ scholars, the paper proposes that the generalized study of combustion is a key to contextualizing human energetic practices within a broader ‘economy’ of terrestrial and cosmic energy flows. We examine the relatively recent turn towards fossil-fuelled ‘internal (...) combustion’ in the light of a much longer human history of ‘broadcast’ burning of vegetation and of artisanal pyrotechnologies – the use of heat to transform diverse materials. A combustion-centred analysis, it is argued, brings human collective life into closer contact with the geochemical and geologic conditions of earthly existence, while also pointing to the significance of explorative, experimental and even playful dispositions towards energy and matter. (shrink)